SCHEMBL7602161

SCHEMBL7602161

CCCC(CCC)C1(c2ccc(C#N)cc2)CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 15/20 0.41
SLC6A4 P31645 14/20 0.41
CYP2A6 P11509 1/20 0.37
CYP19A1 P11511 1/20 0.37
SLC6A2 P23975 2/20 0.35
CTSC P53634 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6891431 0.87 SLC6A3 (0.40) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2
SCHEMBL10586709 0.83 SLC6A3 (0.43) SLC6A3SLC6A4CYP19A1SLC6A2CTSC
SCHEMBL9485781 0.80 SLC6A4 (0.42) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2
SCHEMBL9485946 0.74 SLC6A3 (0.38) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2
SCHEMBL4820101 0.73 CYP2A6 (0.40) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2
SCHEMBL11138914 0.72 CYP2A6 (0.42) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2
SCHEMBL7855240 0.72 SLC6A4 (0.40) SLC6A3SLC6A4SLC6A2
SCHEMBL14861187 0.71 CNR2 (0.43) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2
SCHEMBL8734995 0.70 CNR2 (0.48) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2
SCHEMBL10606455 0.70 SLC6A3 (0.43) SLC6A3SLC6A4CYP2A6CYP19A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020047103-A1 Liquid crystalline compounds having a silane diyl group, liquid crystal compositions comprising the same and liquid crystal display devices CHISSO PETROCHEMICAL CORPORATION (JP) 2002-04-25 US disclosed
EP-1160251-A2 Liquid crystalline compounds having a silane diyl group, liquid crystal compositions comprising the same and liquid crystal display devices CHISSO CORPORATION (JP) 2001-12-05 EP disclosed