SCHEMBL7602196

SCHEMBL7602196

CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)C3CCOC3)cc2C#N)CC1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7607274 1.00 NPY2R (0.80) NPY2R
SCHEMBL14537895 1.00 NPY2R (0.80) NPY2R
SCHEMBL7602823 0.90 NPY2R (0.79) NPY2R
SCHEMBL7599095 0.89 NPY2R (1.00) NPY2R
SCHEMBL7599226 0.88 NPY2R (0.80) NPY2R
SCHEMBL13873603 0.85 NPY2R (0.57) NPY2R
SCHEMBL13873633 0.82 NPY2R (0.59) NPY2R
SCHEMBL13890091 0.82 NPY2R (0.59) NPY2R
SCHEMBL14537950 0.80 NPY2R (0.62) NPY2R
SCHEMBL7605076 0.80 NPY2R (0.62) NPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183239-B2 Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor JANSSEN PHARMACEUTICA NV (BE) 2012-05-22 US disclosed