SCHEMBL7602734

SCHEMBL7602734

CN(C)c1ncc(Cc2cn(CC(=O)N3CCN(c4ccc(Cl)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7529319 0.93 PLA2G7 (1.00) PLA2G7
SCHEMBL7529704 0.91 PLA2G7 (1.00) PLA2G7
SCHEMBL7532987 0.90 PLA2G7 (1.00) PLA2G7
SCHEMBL7529871 0.90 PLA2G7 (0.81) PLA2G7
SCHEMBL7532169 0.89 PLA2G7 (1.00) PLA2G7
SCHEMBL7527319 0.89 PLA2G7 (1.00) PLA2G7
SCHEMBL7534687 0.89 PLA2G7 (1.00) PLA2G7
SCHEMBL7524836 0.88 PLA2G7 (0.87) PLA2G7
SCHEMBL7527380 0.88 PLA2G7 (0.81) PLA2G7
SCHEMBL7583537 0.87 PLA2G7 (0.86) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1173424-A1 PYRIMIDINE COMPOUNDS SMITHKLINE BEECHAM PLC (GB) 2002-01-23 EP disclosed
WO-2000066566-A1 PYRIMIDINE COMPOUNDS SMITHKLINE BEECHAM PLC (GB) 2000-11-09 WO disclosed