SCHEMBL7602822

SCHEMBL7602822

Cc1ccc(S(=O)(=O)NC(=O)Nc2cccc(C(=O)OCCCNC(=O)N(S)C(C)(C)C)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.44
TCF4 P15884 1/20 0.43
CTNNB1 P35222 1/20 0.43
TP53 P04637 2/20 0.43
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP2C9 P11712 2/20 0.41
ALB P02768 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP9 P14780 2/20 0.41
MMP8 P22894 2/20 0.41
MMP13 P45452 2/20 0.41
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7601714 0.97 LMNA (0.44) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7599741 0.91 LMNA (0.47) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7598242 0.90 LMNA (0.46) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7596313 0.90 PPARG (0.47) LMNATP53KMT2AMEN1SMN1; SMN2
SCHEMBL7601032 0.89 LMNA (0.45) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7601301 0.88 LMNA (0.46) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7596702 0.88 LMNA (0.45) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7596599 0.88 LMNA (0.48) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7597925 0.87 LMNA (0.45) LMNATCF4CTNNB1TP53KMT2A
SCHEMBL7601834 0.87 PPARG (0.46) LMNATP53KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed