Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322609 | 0.94 | PSEN1 (0.43) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL383065 | 0.90 | PSEN1 (0.47) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6140474 | 0.88 | PTPN1 (0.45) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL6140187 | 0.88 | PTPN1 (0.45) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL6140552 | 0.88 | MAPT (0.46) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL6140151 | 0.88 | MAPT (0.46) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL8319103 | 0.88 | MAPT (0.40) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL8651662 | 0.87 | PSEN1 (0.41) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL8647752 | 0.87 | PSEN1 (0.43) | MAPTHTTPSEN1PSEN2APH1B | |
| SCHEMBL133377 | 0.85 | PTPN1 (0.51) | MAPTPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492075-B1 | COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST | ADVANCED MICRO DEVICES, INC. | 2002-12-10 | — | — | US | disclosed |
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |