Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR1E | P28566 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602752 | 0.91 | PTGES (0.42) | PTGER3PTGESACKR3ALDH1A1KDM4E | |
| SCHEMBL1178596 | 0.90 | PTGES (0.43) | PTGER3PTGESACKR3ALDH1A1KDM4E | |
| SCHEMBL1178323 | 0.88 | PTGER3 (0.39) | PTGER3PTGESACKR3ALDH1A1KDM4E | |
| Bicarbonate SCHEMBL3703539 | 0.82 | PTGES (0.45) | PTGER3PTGESACKR3ALDH1A1KDM4E | |
| SCHEMBL1178138 | 0.81 | PTGES (0.46) | PTGER3PTGESACKR3ALDH1A1KDM4E | |
| SCHEMBL1177281 | 0.80 | PTGES (0.41) | PTGER3PTGESACKR3ALDH1A1KDM4E | |
| SCHEMBL7602660 | 0.80 | PTGES (0.40) | PTGESACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1178537 | 0.78 | PTGES (0.42) | PTGESACKR3MAPTMEN1LMNA | |
| SCHEMBL7604036 | 0.78 | CYP1A2 (0.49) | PTGESACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7601092 | 0.78 | CYP1A2 (0.49) | PTGESACKR3CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |