Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | THRB | P10828 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504532 | 0.94 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8502876 | 0.88 | TSHR (0.86) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL6765409 | 0.88 | TSHR (0.86) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12112388 | 0.86 | TSHR (0.69) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12112390 | 0.86 | TSHR (0.63) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8636795 | 0.85 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12701599 | 0.85 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL25514 | 0.85 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4602612 | 0.85 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL18134826 | 0.85 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304554-B2 | Compound, composition and thin film | FUJIFILM CORPORATION (JP) | 2012-11-06 | — | — | US | disclosed |
| US-20120229734-A1 | OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| US-8184247-B2 | TN-mode liquid crystal display device, optical compensatory film for use therein and method for producing optical compensatory film, and polarizing plate | FUJIFILM CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8164722-B2 | Liquid-crystal display device with at least three optically-anisotropic layers having formulated in-plane retardations | FUJIFILM CORPORATION (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8053040-B2 | Liquid crystal composition, retardation plate, liquid crystal display device, and process for producing retardation plate | FUJIFILM CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| US-8025933-B2 | Optical anisotropic layer | FUJIFILM CORPORATION (JP) | 2011-09-27 | — | — | US | disclosed |
| US-8025936-B2 | Optical compensation film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-09-27 | — | — | US | disclosed |
| US-7968157-B2 | Discotic nematic material, composition, retardation plate, elliptically-polarizing plate and compound | FUJIFILM CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7929089-B2 | Optical compensation film, polarizing plate, and liquid-crystal display device | FUJIFILM CORPORATION (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20110063552-A1 | LIQUID CRYSTAL DISPLAY DEVICE, AND LIQUID CRYSTAL CELL | FUJIFILM CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20090244454-A1 | LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090091691-A1 | OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20090091690-A1 | Optical Compensation Film, Polarizing Plate and Liquid Crystal Display Device | FUJIFILM CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20090068378-A1 | DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND | FUJIFILM CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090033839-A1 | RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING IT | FUJIFILM CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20080291369-A1 | Optical Film, Optical Compensation Film, Polarizing Plate, and Liquid-Crystal Display Device | FUJIFILM CORPORATION (JP) | 2008-11-27 | — | — | US | disclosed |
| US-20080193679-A1 | Optical anisotropic layer | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080113112-A1 | Optical Compensation Film, Method of Producing the Same, and Polarizing Plate and Liquid Crystal Display Device Using the Same | FUJIFILM CORPORATION (JP) | 2008-05-15 | — | — | US | disclosed |
| US-5977277-A | Acrylic ester, novel allyl ether, novel allyl carbonate, acrylic ester polymer, allyl ether polymer, allyl carbonate polymer and polymeric solid electrolyte | MITSUI PETROCHEMICAL INDUSTRIES, LTD (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0896340-A1 | GEL-FORM SOLID POLYMER ELECTROLYTE | Mitsui Chemicals, Inc. (JP) | 1999-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068378-A1 | DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND | H1-2, H1-0, CCNL2 | TSHR 2291/4885ALDH1A1 3847/4885TP53 3006/4885 |
| US-20080193679-A1 | Optical anisotropic layer | YBX1, YBX3, H1-2 | TSHR 2424/4885ALDH1A1 2541/4885TP53 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.