SCHEMBL8504532

SCHEMBL8504532

C=CC(=O)OCCOC(=O)OC

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.61
ALDH1A1 P00352 5/20 0.61
TP53 P04637 3/20 0.61
HIF1A Q16665 3/20 0.61
HSD17B10 Q99714 1/20 0.61
CYP3A4 P08684 2/20 0.56
HPGD P15428 1/20 0.55
THRB P10828 4/20 0.50
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7603067 0.94 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12112388 0.92 TSHR (0.69) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12112390 0.92 TSHR (0.63) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL25822495 0.91 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12112429 0.90 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12112431 0.90 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12267037 0.90 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL15583435 0.87 TSHR (0.47) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5664024 0.86 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL15081556 0.85 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117980349-A Carbonate (meth) acrylate compositions 日油株式会社 2024-05-03 CN disclosed
WO-2023058511-A1 CARBONATE (METH)ACRYLATE COMPOSITION 日油株式会社 2023-04-13 WO disclosed
US-9638849-B2 Liquid crystal compound, optical film, and method for producing optical film FUJIFILM CORPORATION (JP) 2017-05-02 US disclosed
US-9638849-B2 Liquid crystal compound, optical film, and method for producing optical film FUJIFILM CORPORATION (JP) 2017-05-02 US disclosed
US-9505961-B2 Acrylic pressure sensitive adhesive composition, protection film including the same, polarizer and liquid crystal display LG CHEM, LTD. (KR) 2016-11-29 US disclosed
US-20150277007-A1 LIQUID CRYSTAL COMPOUND, OPTICAL FILM, AND METHOD FOR PRODUCING OPTICAL FILM FUJIFILM CORPORATION (JP) 2015-10-01 US disclosed
US-20150277007-A1 LIQUID CRYSTAL COMPOUND, OPTICAL FILM, AND METHOD FOR PRODUCING OPTICAL FILM FUJIFILM CORPORATION (JP) 2015-10-01 US disclosed
US-8304554-B2 Compound, composition and thin film FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20120229734-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-8053040-B2 Liquid crystal composition, retardation plate, liquid crystal display device, and process for producing retardation plate FUJIFILM CORPORATION (JP) 2011-11-08 US disclosed
US-20090091691-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-04-09 US disclosed
US-20090068378-A1 DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
US-20090033839-A1 RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING IT FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080291369-A1 Optical Film, Optical Compensation Film, Polarizing Plate, and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-11-27 US disclosed
US-20080193679-A1 Optical anisotropic layer FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080192191-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080186443-A1 Liquid Crystal Composition, Retardation Plate, and Elliptic Polarizing Plate FUJIFILM CORPORATION (JP) 2008-08-07 US disclosed
US-20080113112-A1 Optical Compensation Film, Method of Producing the Same, and Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-5977277-A Acrylic ester, novel allyl ether, novel allyl carbonate, acrylic ester polymer, allyl ether polymer, allyl carbonate polymer and polymeric solid electrolyte MITSUI PETROCHEMICAL INDUSTRIES, LTD (JP) 1999-11-02 US disclosed
EP-0896340-A1 GEL-FORM SOLID POLYMER ELECTROLYTE Mitsui Chemicals, Inc. (JP) 1999-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068378-A1 DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND H1-2, H1-0, CCNL2 TSHR 2291/4885ALDH1A1 3847/4885TP53 3006/4885
US-20080193679-A1 Optical anisotropic layer YBX1, YBX3, H1-2 TSHR 2424/4885ALDH1A1 2541/4885TP53 4114/4885
US-20150277007-A1 LIQUID CRYSTAL COMPOUND, OPTICAL FILM, AND METHOD FOR PRODUCING OPTICAL FILM CFL1, AUP1, PDE6G TSHR 4721/4885ALDH1A1 1848/4885TP53 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.