SCHEMBL7603203

SCHEMBL7603203

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(Br)c(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.62
MEN1 O00255 6/20 0.62
LMNA P02545 4/20 0.62
MAPT P10636 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
NPC1 O15118 3/20 0.62
HTT P42858 2/20 0.62
HPGD P15428 4/20 0.54
ALOX15 P16050 2/20 0.54
ALOX12 P18054 2/20 0.54
RAB9A P51151 3/20 0.52
ALDH1A1 P00352 3/20 0.50
GAA P10253 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
EPHX1 P07099 1/20 0.46
EPHX2 P34913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30499669 1.00 KMT2A (0.62) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL7603173 0.93 KMT2A (0.52) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL9348738 0.89 MAPT (0.48) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL7607938 0.88 NPC1 (0.48) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL30499699 0.88 NPC1 (0.48) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL30499685 0.87 EPHX1 (0.64) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL7191660 0.87 EPHX1 (0.64) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL8840317 0.85 PPIA (0.46) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL7603457 0.84 KMT2A (0.59) KMT2AMEN1LMNAMAPTNPC1
SCHEMBL9350074 0.83 SMN1; SMN2 (0.62) KMT2AMEN1LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US claimed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed
US-4920135-A NONPHYTOTOXIC, INTERFERE WITH METAMORPHOSIS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1990-04-24 US disclosed
US-4833151-A INTERFERES WITH METAMORPHOSES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-05-23 US disclosed
US-4607044-A Insecticidal use of ureas and thioureas DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1986-08-19 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885LMNA 3523/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885LMNA 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.