SCHEMBL7603230

SCHEMBL7603230

CC(C(=O)C(C)c1ccc(S(=O)(=O)Cl)cc1)c1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
AKR1C3 P42330 4/20 0.40
AKR1C2 P52895 3/20 0.40
PTGS2 P35354 5/20 0.37
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
CA4 P22748 2/20 0.36
FAAH O00519 1/20 0.36
CXCR1 P25024 4/20 0.36
CXCR2 P25025 4/20 0.36
PTGS1 P23219 4/20 0.35
LMNA P02545 2/20 0.35
CYP2C9 P11712 2/20 0.35
ALB P02768 1/20 0.35
ESR1 P03372 1/20 0.35
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758657 0.86 AKR1C3 (0.54) ALDH1A1HSD17B10TDP1AKR1C3AKR1C2
SCHEMBL27536782 0.82 AKR1C3 (0.53) AKR1C3AKR1C2LMNATSHR
SCHEMBL18151426 0.79 CA12 (0.44) ALDH1A1PTGS2CA12CA1CA2
SCHEMBL343985 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1PTGS2CA12
SCHEMBL8469242 0.78 APP (0.47) ALDH1A1HSD17B10TDP1AKR1C3AKR1C2
SCHEMBL1596452 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1AKR1C3AKR1C2
Hydrochloric Acid SCHEMBL7568273 0.77 ALDH1A1 (0.48) ALDH1A1HSD17B10TDP1PTGS2CA12
SCHEMBL1597018 0.75 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1AKR1C3AKR1C2
SCHEMBL28757949 0.74 TSHR (0.38) ALDH1A1HSD17B10TDP1AKR1C3AKR1C2
SCHEMBL21842108 0.74 ALDH1A1 (0.48) ALDH1A1HSD17B10TDP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770599-B1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS (JP) 2002-08-07 EP disclosed
US-5811571-A HALOGENATING AN AROMATIC OR HETEROAROMATIC METHYL SULFIDE OR METHYL SULFOXIDE IN PRESENCE OF WATER SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-09-22 US disclosed
EP-0770599-A1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-02 EP disclosed