SCHEMBL7603320

SCHEMBL7603320

CC(CCN1CCCC1=O)N1CCOCC1=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
PKM P14618 1/20 0.43
LMNA P02545 2/20 0.36
ADRA1D P25100 2/20 0.35
ADRA1A P35348 2/20 0.35
ADRA1B P35368 2/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 2/20 0.33
MALT1 Q9UDY8 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7603997 0.96 KMT2A (0.40) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL7603739 0.95 KMT2A (0.39) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL7603122 0.89 PIK3CD (0.37) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL7607202 0.87 PIK3CD (0.45) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL7605230 0.85 CHRM2 (0.35) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL7603856 0.84 CHRM2 (0.35) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL1705435 0.84 PIK3CD (0.53) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL7603912 0.83 PIK3CD (0.41) PIK3CDKMT2AMEN1PKMLMNA
SCHEMBL7605032 0.83 ACHE (0.32)
SCHEMBL7606074 0.82 PIK3CD (0.40) PIK3CDKMT2AMEN1PKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934080-B1 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF BASF AG (DE) 2002-06-12 EP claimed
EP-0934080-B1 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF BASF AG (DE) 2002-06-12 EP disclosed