SCHEMBL9516767

SCHEMBL9516767

COC(F)(F)/C(Cl)=C/C1C(OC=O)C1(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7173074 0.85 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL3367420 0.85 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL11492765 0.85 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL8027463 0.85 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL7603511 0.85 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL9515605 0.82 MEN1 (0.32) MEN1KMT2ATDP1
SCHEMBL9516624 0.80 MEN1 (0.31) MEN1KMT2ATDP1
SCHEMBL10828119 0.79 HPGD (0.31)
SCHEMBL10828326 0.79 HPGD (0.31)
SCHEMBL7174560 0.79 HPGD (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0258815-B1 DERIVATIVES OF 2,2-DIMETHYL-CYCLOPROPANECARBOXYLIC ACID ISTITUTO GUIDO DONEGANI S.p.A. (IT) 1993-04-07 EP disclosed