Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832035 | 0.74 | GABRA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL293449 | 0.67 | — | — | |
| SCHEMBL10457411 | 0.64 | GABRA1 (0.37) | GABRA1GABRB2 | |
| SCHEMBL293695 | 0.61 | — | — | |
| SCHEMBL2285787 | 0.59 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL2140671 | 0.59 | — | — | |
| SCHEMBL27743275 | 0.59 | — | — | |
| SCHEMBL743996 | 0.58 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL6024080 | 0.58 | — | — | |
| SCHEMBL11784144 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242432-A1 | PHOSPHONIC ACID DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B (PTP-1B) | MERCK FROSST CANADA INC. (CA) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046205-A1 | PHOSPHONIC ACID DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B (PTP-1B) | MERCK FROSST CANADA & CO. (CA) | 2001-06-28 | — | — | WO | disclosed |