⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6291532 | 0.97 | — | — | |
| SCHEMBL6291542 | 0.77 | — | — | |
| SCHEMBL15647845 | 0.73 | — | — | |
| SCHEMBL10355690 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL15647118 | 0.71 | — | — | |
| SCHEMBL18583709 | 0.69 | SLC6A4 (0.35) | — | |
| SCHEMBL6138301 | 0.69 | — | — | |
| SCHEMBL2843814 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL34474173 | 0.67 | OPRM1 (0.31) | — | |
| SCHEMBL6138317 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| WO-2021252692-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| US-20140213508-A1 | ANTIVIRAL MACROCYCLES | SCYNEXIS, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140212381-A1 | MACROCYCLES | SCYNEXIS, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| EP-1170281-A1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | LES LABORATOIRES SERVIER (FR) | 2002-01-09 | — | — | EP | disclosed |