SCHEMBL7604153

SCHEMBL7604153

CCC(c1ccc2c(c1)Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2.[Zr]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.42
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PNMT P11086 1/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 3/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SRD5A2 P31213 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7609070 0.96 CYP17A1 (0.44) CYP17A1ALDH1A1TSHRATMNPSR1
SCHEMBL6674901 0.85 PNMT (0.49) ALDH1A1TSHRATMNPSR1PNMT
SCHEMBL6675789 0.77 PNMT (0.46) ALDH1A1PNMTNPC1RAB9ACYP1A2
SCHEMBL7612685 0.76 PNMT (0.38) ALDH1A1TSHRATMNPSR1PNMT
SCHEMBL6671930 0.76 PNMT (0.40) PNMTNPC1RAB9ASRD5A2HTR2B
SCHEMBL28964213 0.75 CYP17A1 (0.52) CYP17A1ALDH1A1TSHRATMNPSR1
SCHEMBL6676496 0.74 PNMT (0.44) PNMTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL1611366 0.74 PNMT (0.46) ALDH1A1TSHRATMNPSR1PNMT
SCHEMBL10781023 0.74 PNMT (0.50) ALDH1A1PNMTNPC1RAB9AKDM4E
SCHEMBL6674618 0.73 PNMT (0.43) ALDH1A1PNMTNPC1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP claimed