⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982314 | 0.81 | MAPK1 (0.65) | — | |
| SCHEMBL1040994 | 0.79 | — | — | |
| SCHEMBL2087163 | 0.79 | — | — | |
| SCHEMBL35599 | 0.79 | — | — | |
| Terbuprol SCHEMBL16001415 | 0.78 | MAPK1 (0.54) | — | |
| Terbuprol SCHEMBL16001420 | 0.78 | MAPK1 (0.54) | — | |
| Terbuprol SCHEMBL1815375 | 0.78 | MAPK1 (0.54) | — | |
| SCHEMBL19415051 | 0.77 | — | — | |
| SCHEMBL13203576 | 0.77 | MAPK1 (0.59) | — | |
| SCHEMBL812276 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224256-A1 | DETERGENTS OR CLEANING AGENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001032820-A1 | DETERGENTS OR CLEANING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-10 | — | — | WO | claimed |
| US-9206174-B2 | 5-anilinoimidazopyridines and methods of use | GENENTECH, INC. (US) | 2015-12-08 | — | — | US | disclosed |
| US-9206174-B2 | 5-anilinoimidazopyridines and methods of use | GENENTECH, INC. (US) | 2015-12-08 | — | — | US | disclosed |
| US-20130150584-A1 | 5-ANILINOIMIDAZOPYRIDINES AND METHODS OF USE | GENENTECH, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-7923456-B2 | 5-anilinoimidazo[1,5-a]-pyridines inhibitors of MEK kinase | GENENTECH, INC. (US) | 2011-04-12 | — | — | US | disclosed |
| US-7923456-B2 | 5-anilinoimidazo[1,5-a]-pyridines inhibitors of MEK kinase | GENENTECH, INC. (US) | 2011-04-12 | — | — | US | disclosed |
| US-20100004269-A1 | 5-ANILINOIMIDAZOPYRIDINES AND METHODS OF USE | GENENTECH, INC. (US) | 2010-01-07 | — | — | US | disclosed |
| US-20100004269-A1 | 5-ANILINOIMIDAZOPYRIDINES AND METHODS OF USE | GENENTECH, INC. (US) | 2010-01-07 | — | — | US | disclosed |