SCHEMBL7604199

SCHEMBL7604199

CC(C)(C)c1cccc2c1C(CCC1c3ccccc3-c3cccc(C(C)(C)C)c31)c1ccccc1-2.[Zr]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.40
CA2 P00918 2/20 0.34
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 1/20 0.33
GPR3 P46089 1/20 0.32
TDO2 P48775 1/20 0.32
ACHE P22303 2/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5346148 0.97 HTR2A (0.40) HTR2ACA2ALDH1A1TSHRTDP1
SCHEMBL8857018 0.90 HTR2A (0.35) HTR2ACA2ACHECHRM2HTR1A
Hydrochloric Acid SCHEMBL7606454 0.88 HTR2A (0.34) HTR2A
SCHEMBL29565918 0.79 CA2 (0.36) HTR2ACA2ALDH1A1TSHRTDP1
Hydrochloric Acid SCHEMBL5351373 0.79 HTR2A (0.35) HTR2ACA2ALDH1A1TSHRTDP1
Hydrochloric Acid SCHEMBL5352797 0.79 HTR2A (0.35) HTR2ACA2ALDH1A1TSHRTDP1
SCHEMBL5177268 0.77 CA2 (0.38) HTR2ACA2ALDH1A1TSHRTDP1
SCHEMBL7606771 0.77 HTR2A (0.44) HTR2ACA2ALDH1A1CA1GPR3
Hydrochloric Acid SCHEMBL5352133 0.76 HTR2A (0.42) HTR2ACA2CA1GPR3TDO2
Hydrochloric Acid SCHEMBL5352775 0.76 HTR2A (0.42) HTR2ACA2CA1GPR3TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP claimed