Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480473 | 0.82 | TSHR (0.53) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL5480477 | 0.82 | TSHR (0.53) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL5857882 | 0.81 | TSHR (0.51) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL5859950 | 0.81 | TSHR (0.51) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL7636048 | 0.79 | TSHR (0.45) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL7604319 | 0.77 | TSHR (0.52) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL7593268 | 0.76 | ADRB3 (0.46) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL5479233 | 0.74 | ADRB3 (0.54) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL5485060 | 0.74 | ADRB3 (0.54) | TSHRADRB3ADRB2ADRB1BCHE | |
| SCHEMBL5858588 | 0.72 | TSHR (0.48) | TSHRADRB3ADRB2ADRB1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458824-B1 | (3-((2R)-(((2R)-(3-CHLOROPHENYL)-2-HYDROXYETHYL)AMINO)PROPYL)-1H-INDOL-7-YLOXY)ACETIC ACID CRYSTAL SOLIDS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-1235801-A2 | SOLID PHARMACEUTICAL PREPARATION | Dainippon Pharmaceutical Co., Ltd. (JP) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001040182-A2 | SOLID PHARMACEUTICAL PREPARATION | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |