Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604489 | 1.00 | ASGR1 (0.31) | ASGR1 | |
| SCHEMBL6291536 | 0.82 | HCAR2 (0.38) | ASGR1 | |
| SCHEMBL6291538 | 0.82 | HCAR2 (0.38) | ASGR1 | |
| SCHEMBL7607211 | 0.80 | ASGR1 (0.33) | ASGR1 | |
| SCHEMBL23539500 | 0.79 | — | — | |
| SCHEMBL5328352 | 0.73 | HDAC6 (0.30) | — | |
| SCHEMBL31089436 | 0.72 | — | — | |
| SCHEMBL25075599 | 0.71 | HDAC6 (0.33) | ASGR1 | |
| SCHEMBL1771222 | 0.70 | FABP4 (0.35) | ASGR1 | |
| SCHEMBL28024842 | 0.70 | ASGR1 (0.33) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170281-A1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | LES LABORATOIRES SERVIER (FR) | 2002-01-09 | — | — | EP | disclosed |