Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606630 | 0.99 | KDM4E (0.31) | ALDH1A1KDM4ELMNAMAPK1WDR5 | |
| Hydrochloric Acid SCHEMBL7605151 | 0.98 | KDM4E (0.30) | ALDH1A1KDM4ELMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL7937828 | 0.90 | KDM4E (0.33) | ALDH1A1KDM4ELMNAMAPK1 | |
| SCHEMBL5174322 | 0.86 | MAPT (0.33) | MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7195300 | 0.83 | MAPT (0.31) | MEN1MAPTKMT2A | |
| SCHEMBL7608411 | 0.82 | MEN1 (0.32) | ALDH1A1KDM4ELMNAMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL7940430 | 0.81 | MEN1 (0.31) | ALDH1A1MEN1MAPTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL7603013 | 0.81 | MEN1 (0.31) | ALDH1A1MEN1MAPTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL7939984 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7939283 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672675-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0672675-A1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5451649-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-09-19 | — | — | US | disclosed |