Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316873 | 0.91 | CYP1B1 (0.57) | MEN1KMT2APDE4ACYP1B1PPARG | |
| Recoflavone SCHEMBL29406117 | 0.88 | ABCB1 (0.59) | MEN1KMT2AABCB1CYP1B1ABCG2 | |
| Recoflavone SCHEMBL2483541 | 0.88 | ABCB1 (0.59) | MEN1KMT2AABCB1CYP1B1ABCG2 | |
| Recoflavone SCHEMBL7603767 | 0.88 | ABCB1 (0.58) | MEN1KMT2AABCB1CYP1B1ABCG2 | |
| Recoflavone SCHEMBL2483546 | 0.88 | ABCB1 (0.58) | MEN1KMT2AABCB1CYP1B1ABCG2 | |
| Recoflavone SCHEMBL4829847 | 0.86 | ABCB1 (0.56) | MEN1KMT2AABCB1CYP1B1ABCG2 | |
| SCHEMBL8427265 | 0.85 | KDM4E (0.59) | MEN1KMT2AABCB1CYP1B1ABCG2 | |
| SCHEMBL7303645 | 0.84 | CYP1B1 (0.57) | MEN1KMT2APDE4ACYP1B1TP53 | |
| SCHEMBL7311118 | 0.84 | CYP1B1 (0.57) | MEN1KMT2APDE4ACYP1B1TP53 | |
| SCHEMBL7605191 | 0.83 | CYP1B1 (0.72) | MEN1KMT2AABCB1CYP1B1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915864-B1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARM CO LTD (KR) | 2002-09-04 | — | — | EP | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |