Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Recoflavone SCHEMBL29406117 | 1.00 | ABCB1 (0.59) | ABCB1MEN1KMT2AABCG2TP53 | |
| Recoflavone SCHEMBL7603767 | 0.99 | ABCB1 (0.58) | ABCB1MEN1KMT2AABCG2TP53 | |
| Recoflavone SCHEMBL2483546 | 0.99 | ABCB1 (0.58) | ABCB1MEN1KMT2AABCG2TP53 | |
| Recoflavone SCHEMBL4829847 | 0.97 | ABCB1 (0.56) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL8427265 | 0.94 | KDM4E (0.59) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL7605191 | 0.91 | CYP1B1 (0.72) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL2481857 | 0.91 | MEN1 (0.59) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL7609527 | 0.91 | KDM4E (0.53) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL14178905 | 0.90 | ABCB1 (0.58) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL7603078 | 0.90 | L3MBTL1 (0.65) | ABCB1MEN1KMT2AABCG2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170857-B1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULANT OF MUCUS SECRETION, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG A PHARM CO LTD (KR) | 2011-10-19 | — | — | EP | claimed |
| EP-1660074-B1 | 7-CARBOXYMETHYLOXY-3 , 4 , 5-TRIMETHOXY FLAVONE MONOHYD RATE, THE PREPARATION METHOD AND USES THEREOF | DONG A PHARM CO LTD (KR) | 2009-12-16 | — | — | EP | claimed |
| EP-2065375-A1 | A process for the preparation of 7-carboxymethyloxy-3',4', 5-trimethoxy flavone | Dong-A Pharmaceutical Co., Ltd. (KR) | 2009-06-03 | — | — | EP | claimed |
| US-7371775-B2 | 7-carboxymethyloxy-3′,4′,5-trimethoxy flavone monohydrate, the preparation method and uses thereof | DONG-A PHARMACEUTICALS CO., LTD (KR) | 2008-05-13 | — | — | US | claimed |
| US-20060178428-A1 | 7-Carboxymethyloxy-3',4',5-trimethoxy flavone monohydrate, the preparation method and uses thereof | DONG-A PHARMACEUTICAL CO., LTD (KR) | 2006-08-10 | — | — | US | claimed |
| EP-0915864-B1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARM CO LTD (KR) | 2002-09-04 | — | — | EP | claimed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | claimed |
| US-20250082603-A1 | OPHTHALMIC COMPOSITION CONTAINING RECOFLAVONE FOR THE TREATMENT OF DRY EYE DISEASE AND METHOD FOR PREPARING THE SAME | GL PHARMTECH CORP. (KR) | 2025-03-13 | — | — | US | disclosed |
| US-20250082602-A1 | OPHTHALMIC COMPOSITION CONTAINING RECOFLAVONE FOR THE TREATMENT OF DRY EYE DISEASE | GL PHARMTECH CORP. (KR) | 2025-03-13 | — | — | US | disclosed |
| CN-117794515-A | Eye drop composition comprising releavance flavone for treating dry eye syndrome and method for preparing the same | 格里医药科技公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117794514-A | Eye drop composition comprising a releaf flavonoid for treating dry eye | 格里医药科技公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-4342452-A1 | EYE DROP COMPOSITION COMPRISING RECOFLAVONE FOR TREATMENT OF XEROPHTHALMIA | GL Pharmtech Corp. (KR) | 2024-03-27 | — | — | EP | disclosed |
| EP-4342453-A1 | EYE DROP COMPOSITION FOR TREATING DRY EYE SYNDROME CONTAINING RECOFLAVONE AND METHOD FOR PREPARING SAME | GL Pharmtech Corp. (KR) | 2024-03-27 | — | — | EP | disclosed |
| US-20060178428-A1 | 7-Carboxymethyloxy-3',4',5-trimethoxy flavone monohydrate, the preparation method and uses thereof | DONG-A PHARMACEUTICAL CO., LTD (KR) | 2006-08-10 | — | — | US | disclosed |
| EP-1660074-A1 | 7-CARBOXYMETHYLOXY-3 , 4 , 5-TRIMETHOXY FLAVONE MONOHYD RATE, THE PREPARATION METHOD AND USES THEREOF | Dong-A Pharmaceutical Co., Ltd. (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1660074-A1 | 7-CARBOXYMETHYLOXY-3 , 4 , 5-TRIMETHOXY FLAVONE MONOHYD RATE, THE PREPARATION METHOD AND USES THEREOF | Dong-A Pharmaceutical Co., Ltd. (KR) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005023244-A1 | 7-CARBOXYMETHYLOXY-3', 4', 5-TRIMETHOXY FLAVONE MONOHYDRATE, THE PREPARATION METHOD AND USES THEREOF | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 2005-03-17 | — | — | WO | disclosed |
| WO-2005023244-A1 | 7-CARBOXYMETHYLOXY-3', 4', 5-TRIMETHOXY FLAVONE MONOHYDRATE, THE PREPARATION METHOD AND USES THEREOF | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 2005-03-17 | — | — | WO | disclosed |
| EP-0915864-B1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARM CO LTD (KR) | 2002-09-04 | — | — | EP | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250082602-A1 | OPHTHALMIC COMPOSITION CONTAINING RECOFLAVONE FOR THE TREATMENT OF DRY EYE DISEASE | NR1H4, NR1H2, NR1H3 | ABCB1 407/4885MEN1 4875/4885KMT2A 4578/4885 |
| US-20060178428-A1 | 7-Carboxymethyloxy-3',4',5-trimethoxy flavone monohydrate, the preparation method and uses thereof | SI, MLN, TET2 | ABCB1 735/4885MEN1 1448/4885KMT2A 1990/4885 |
| US-20250082603-A1 | OPHTHALMIC COMPOSITION CONTAINING RECOFLAVONE FOR THE TREATMENT OF DRY EYE DISEASE AND METHOD FOR PREPARING THE SAME | CYP46A1, NR1H4, NR1H2 | ABCB1 553/4885MEN1 4845/4885KMT2A 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.