Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.66 |
| ▸ | FNTB | P49356 | 10/20 | 0.66 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605084 | 1.00 | FNTA (0.66) | FNTAFNTBPGGT1BTDP1 | |
| Hydrochloric Acid SCHEMBL6772289 | 0.99 | FNTA (0.65) | FNTAFNTBPGGT1BTDP1 | |
| Hydrochloric Acid SCHEMBL6772283 | 0.99 | FNTA (0.65) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL6782074 | 0.92 | FNTA (0.63) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL6782079 | 0.92 | FNTA (0.63) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7610099 | 0.91 | FNTA (0.60) | FNTAFNTBPGGT1BTDP1 | |
| Hydrochloric Acid SCHEMBL6777613 | 0.91 | FNTA (0.59) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7605772 | 0.88 | FNTA (0.58) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7605763 | 0.88 | FNTA (0.58) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL6778067 | 0.88 | FNTA (0.67) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | UNIVERSITY OF PITTSBURGH (US) | 2002-12-19 | — | — | US | claimed |
| US-20160375041-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | TABACZYNSKI DAVID A (US) | 2016-12-29 | — | — | US | disclosed |
| US-20160303146-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | TABACZYNSKI DAVID A (US) | 2016-10-20 | — | — | US | disclosed |
| WO-2015089349-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015084721-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | LANCL1, FNTB, DHCR7 | FNTA 20/4885FNTB 2/4885PGGT1B 1021/4885 |
| US-20160375041-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | GGPS1, FDPS, COASY | FNTA 4/4885FNTB 15/4885PGGT1B 343/4885 |
| US-20160303146-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | GGPS1, FDPS, COASY | FNTA 4/4885FNTB 10/4885PGGT1B 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.