Triphosphate

Triphosphate

SCHEMBL76054

Nc1nc2nc[nH]c2c(=O)[nH]1.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PNP P00491 3/20 0.70
POLG P54098 2/20 0.46
POLB P06746 2/20 0.46
POLA1 P09884 1/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GDA Q9Y2T3 1/20 0.43
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41
DPP4 P27487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL12813216 1.00 PNP (0.70) PNPPOLGPOLBPOLA1ALDH1A1
Guanine SCHEMBL29844110 0.99 PNP (0.68) PNPPOLGPOLBPOLA1ALDH1A1
Triphosphate SCHEMBL28841044 0.99 PNP (0.68) PNPPOLGPOLBPOLA1ALDH1A1
Guanine SCHEMBL101893 0.94 PNP (0.74) PNPPOLGPOLBPOLA1ALDH1A1
Guanine SCHEMBL6910699 0.89 PNP (0.59) PNPPOLGPOLBPOLA1ALDH1A1
Guanine SCHEMBL663746 0.89 PNP (0.84) PNPALDH1A1KDM4EMEN1MAPT
Guanine SCHEMBL76056 0.89 PNP (0.84) PNPALDH1A1KDM4EMEN1MAPT
Guanine SCHEMBL101895 0.89 PNP (0.84) PNPALDH1A1KDM4EMEN1MAPT
Guanine SCHEMBL5372458 0.87 PNP (0.81) PNPALDH1A1KDM4EMEN1MAPT
Guanine SCHEMBL28840730 0.86 PNP (0.79) PNPALDH1A1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1038 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4596713-A1 DNA WITH ENHANCED RESISTANCE AGAINST EXONUCLEASES AND METHODS FOR THE PRODUCTION THEREOF 4basebio UK Ltd (GB) 2025-08-06 EP claimed
WO-2024250923-A1 CHEMICALLY MODIFIED NUCLEOSIDE, CHEMICALLY MODIFIED NUCLEOSIDE TRIPHOSPHATE AND USE THEREOF 中国科学院深圳先进技术研究院 2024-12-12 WO claimed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US claimed
EP-4146285-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2023-03-15 EP claimed
EP-4087611-A1 SHP2 INHIBITOR DOSING AND METHODS OF TREATING CANCER Revolution Medicines, Inc. (US) 2022-11-16 EP claimed
CN-115052635-A Circular RNA compositions and methods 奥纳治疗公司 2022-09-13 CN claimed
CN-114929279-A Methods of administering SHP2 inhibitors and treating cancer 锐新医药公司 2022-08-19 CN claimed
EP-3920976-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2021-12-15 EP claimed
WO-2021226597-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-11-11 WO claimed
WO-2021113777-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-06-10 WO claimed
EP-0629706-B1 Improved method for nucleic acid amplification by NASBA BIOMERIEUX BV (NL) 2004-10-06 EP claimed
CN-1415761-A Detection method of DNA methylation UNIV DONGNAN (CN) 2003-05-07 CN claimed
EP-1082344-B1 GLYCOPROTEINS HAVING LIPID MOBILISING PROPERTIES AND THERAPEUTIC APPLICATIONS THEREOF TISDALE MICHAEL JOHN (GB) 2003-03-19 EP claimed
EP-1082344-A2 GLYCOPROTEINS HAVING LIPID MOBILISING PROPERTIES AND THERAPEUTIC APPLICATIONS THEREOF Tisdale, Michael John (GB) 2001-03-14 EP claimed
EP-1032700-A1 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES New York Medical College (US) 2000-09-06 EP claimed
WO-1999062939-A2 GLYCOPROTEINS HAVING LIPID MOBILISING PROPERTIES AND THERAPEUTIC APPLICATIONS THEREOF TISDALE MICHAEL JOHN (GB) 1999-12-09 WO claimed
WO-1999006592-A9 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES NEW YORK MEDICAL COLLEGE (US) 1999-05-06 WO claimed
WO-1999006592-A1 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES NEW YORK MEDICAL COLLEGE (US) 1999-02-11 WO claimed
US-5654142-A Method for nucleic acid amplification using inosine triphosphates to partially replace guanosine triphosphates in the synthesis of multiple RNA copies AKZO NOBEL N.V. (NL) 1997-08-05 US claimed
EP-0629706-A2 Improved method for nucleic acid amplification Akzo Nobel N.V. (NL) 1994-12-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB PNP 2635/4885POLG 1060/4885POLB 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.