HNRNPA1

Heterogeneous nuclear ribonucleoprotein A1 · P09651 · HNRNPA1 on Sugi Atlas →

3,653 patent compounds predicted against HNRNPA1, 3,233 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Camptothecin (SCHEMBL6038)	1.00	1/20
Camptothecin (SCHEMBL788063)	1.00	1/20
Camptothecin (SCHEMBL2298909)	1.00	1/20
Camptothecin (SCHEMBL4304557)	1.00	1/20
Camptothecin (SCHEMBL548833)	0.98	1/20
Camptothecin (SCHEMBL2866043)	0.98	1/20
Camptothecin (SCHEMBL3117386)	0.98	1/20
Camptothecin (SCHEMBL3651897)	0.98	1/20
Camptothecin (SCHEMBL6006531)	0.98	1/20
Camptothecin (SCHEMBL2043369)	0.96	1/20
Camptothecin (SCHEMBL5967412)	0.95	1/20
Camptothecin (SCHEMBL1980674)	0.93	1/20
Camptothecin (SCHEMBL2864815)	0.93	1/20
Camptothecin (SCHEMBL1618774)	0.91	1/20
Camptothecin (SCHEMBL5491504)	0.90	1/20
Camptothecin (SCHEMBL4552875)	0.85	1/20
Camptothecin (SCHEMBL4471936)	0.83	1/20
Camptothecin (SCHEMBL4473995)	0.83	1/20
Hydroxycamptothecin (SCHEMBL25875)	0.80	1/20
SCHEMBL935913	0.80	1/20

Clinical trials — most relevant to HNRNPA1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure	PHASE2	COMPLETED
Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors	PHASE1	ACTIVE_NOT_RECRUITING
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs	nan	UNKNOWN
Longitudinal Study of Neurogenetic Disorders	nan	RECRUITING
Diagnosis of Inflammatory Bowel Disease	nan	NOT_YET_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
International PPB/DICER1 Registry	nan	RECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
NFC Changes in SLE Patients and Its Correlation With Anti-U1RNPAntibodies and Disease Activity	nan	UNKNOWN
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing	nan	RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Immunophenotyping and Xist Gene in AML	nan	UNKNOWN
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients	nan	UNKNOWN
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study	nan	RECRUITING
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome	nan	ACTIVE_NOT_RECRUITING
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia	nan	NOT_YET_RECRUITING
Mechanisms of Cell Death in Spinal Muscular Atrophy	nan	COMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
Risk of HCC in Cirrhotic Patients Post DAAs Ttt	nan	UNKNOWN
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer	nan	COMPLETED
Identification of New FTLD Genes	nan	UNKNOWN
Hippotherapy in Children With Spinal Muscular Atrophy	nan	RECRUITING
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients	nan	UNKNOWN
Home Monitoring of Adult Patients With SMA: a Pilot Multicenter Validation Study	nan	UNKNOWN
Genetics of Familial and Sporadic ALS	nan	COMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes	nan	UNKNOWN
Molecular Disease Profile of Hematological Malignancies	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a HNRNPA1 binder may also engage these)

Protein	Name	Similarity
Q32P51	—	1.000	Q32P51 →
Q5RBU8	—	1.000	Q5RBU8 →
A7VJC2	—	1.000	A7VJC2 →
Q28521	—	0.998	Q28521 →
HNRNPA3	Heterogeneous nuclear ribonucleoprotein A3	0.998	landscape →
P17130	—	0.997	P17130 →
A5A6H4	—	0.997	A5A6H4 →
P09867	—	0.997	P09867 →
P04256	—	0.997	P04256 →
A0A2R8Y4L2	—	0.997	A0A2R8Y4L2 →
P51992	—	0.996	P51992 →
Q8BG05	—	0.996	Q8BG05 →
Q9TTV2	—	0.996	Q9TTV2 →
P49312	—	0.996	P49312 →
Q6URK4	—	0.995	Q6URK4 →
P51989	—	0.994	P51989 →
HNRNPA2B1	Heterogeneous nuclear ribonucleoproteins A2/B1	0.994	landscape →
Q2HJ60	—	0.993	Q2HJ60 →
P51968	—	0.993	P51968 →
P51990	—	0.993	P51990 →
O88569	—	0.993	O88569 →
P21522	—	0.991	P21522 →
P48810	—	0.991	P48810 →
HNRNPA0	Heterogeneous nuclear ribonucleoprotein A0	0.990	landscape →
Q22037	—	0.985	Q22037 →
P07909	—	0.983	P07909 →
Q9CX86	—	0.983	Q9CX86 →
Q27294	—	0.982	Q27294 →
Q94KD0	—	0.981	Q94KD0 →
RBM3	RNA-binding protein 3	0.979	landscape →