Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.87 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881351 | 0.93 | PGR (1.00) | PGR | |
| SCHEMBL3872475 | 0.93 | PGR (0.74) | PGRNR3C1NR3C2AR | |
| SCHEMBL3870520 | 0.83 | PGR (1.00) | PGR | |
| SCHEMBL3871809 | 0.83 | PGR (0.82) | PGRNR3C1NR3C2AR | |
| SCHEMBL3870564 | 0.78 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL3871920 | 0.78 | PGR (1.00) | PGR | |
| SCHEMBL3871662 | 0.77 | PGR (0.73) | PGRNR3C1NR3C2AR | |
| SCHEMBL3873313 | 0.77 | PGR (1.00) | PGR | |
| SCHEMBL14144952 | 0.77 | PGR (0.73) | PGRNR3C1NR3C2AR | |
| SCHEMBL3870572 | 0.77 | PGR (1.00) | PGRNR3C1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175411-A1 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | American Home Products Corporation (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066570-A1 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |