Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.61 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606373 | 0.88 | FDPS (0.70) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3361664 | 0.80 | FDPS (0.59) | FDPSGGPS1TSHR | |
| SCHEMBL10360509 | 0.80 | FDPS (0.59) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7263779 | 0.79 | FDPS (0.58) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3419952 | 0.77 | FDPS (0.66) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3846830 | 0.76 | FDPS (1.00) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7264380 | 0.74 | FDPS (0.67) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3075655 | 0.74 | FDPS (0.67) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27514707 | 0.74 | FDPS (0.51) | FDPSGGPS1CYP1A2CYP2C9CYP2C19 | |
| Phosphoric Acid SCHEMBL8654813 | 0.73 | FDPS (0.50) | FDPSPTPN1TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916679-B1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-0916679-A1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | Solvay Pharmaceuticals GmbH (DE) | 1999-05-19 | — | — | EP | disclosed |