SCHEMBL7606097

SCHEMBL7606097

C=COC(=O)/C=C\C(=O)ONC(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.39
MAPT P10636 6/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
GAA P10253 2/20 0.32
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ATM Q13315 1/20 0.32
LMNA P02545 1/20 0.31
MDM2 Q00987 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 2/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8712030 0.88 HCAR2 (0.48) HCAR2MAPTGAAALOX15MGAM
SCHEMBL8337805 0.88 HCAR2 (0.48) HCAR2MAPTGAAALOX15MGAM
SCHEMBL27865633 0.81 HCAR2 (0.36) HCAR2MAPTCACNA1BAPBA1GAA
SCHEMBL27447 0.80 TSHR (0.42) HCAR2GAAALOX15MGAMSI
SCHEMBL11055306 0.80 HCAR2 (0.59) HCAR2MAPTATMLMNAMDM2
SCHEMBL5854828 0.80 HCAR2 (0.59) HCAR2MAPTATMLMNAMDM2
SCHEMBL11055272 0.80 HCAR2 (0.59) HCAR2MAPTATMLMNAMDM2
SCHEMBL28659311 0.79 TSHR (0.41) HCAR2GAAALOX15MGAMSI
SCHEMBL1286418 0.79 HCAR2 (0.39) HCAR2MAPTGAAALOX15MGAM
SCHEMBL4078474 0.79 TSHR (0.41) HCAR2GAAALOX15MGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763042-A Reinforcing structural rebar and method of making the same REICHHOLD CHEMICALS, INC. (US) 1998-06-09 US claimed
US-5702816-A Reinforcing structural rebar and method of making the same MARSHALL INDUSTRIES COMPOSITES, INC. (US) 1997-12-30 US claimed
EP-0769088-A1 REINFORCING STRUCTURAL REBAR AND METHOD OF MAKING THE SAME MARSHALL INDUSTRIES COMPOSITES (US) 1997-04-23 EP claimed
WO-1996000824-A1 REINFORCING STRUCTURAL REBAR AND METHOD OF MAKING THE SAME MARSHALL INDUSTRIES COMPOSITES (US) 1996-01-11 WO claimed
US-4188349-A Process for curing unsaturated polyesters utilizing novel initiators ICI AMERICAS INC. (US) 1980-02-12 US claimed
US-6493914-B2 Reinforced composite product and apparatus and method for producing same MARSHALL INDUSTRIES COMPOSITES, INC. 2002-12-17 US disclosed
US-6485660-B1 PULTRUDED NONLINEAR REBAR COMPONENT; REINFORCING COMPOSITE PRODUCT FORMING METHODS ALSO INCLUDE THE USE OF A REMOVABLE OUTER SHELL MARSHALL INDUSTRIES COMPOSITES, INC. 2002-11-26 US disclosed
US-20020031664-A1 Reinforced composite product and apparatus and method for producing same REICHHOLD, INC. 2002-03-14 US disclosed
EP-0929394-B1 REINFORCED COMPOSITE PRODUCT AND APPARATUS AND METHOD FOR PRODUCING SAME MARSHALL IND COMPOSITES (US) 2002-01-30 EP disclosed
US-6316074-B1 Reinforced composite product and apparatus and method for producing same MARSHALL INDUSTRIES COMPOSITES, INC. 2001-11-13 US disclosed
US-6221295-B1 PULTRUDED NONLINEAR REBAR COMPONENT. MARSHALL INDUSTRIES COMPOSITES, INC. 2001-04-24 US disclosed
EP-0929394-A1 REINFORCED COMPOSITE PRODUCT AND APPARATUS AND METHOD FOR PRODUCING SAME MARSHALL INDUSTRIES COMPOSITES (US) 1999-07-21 EP disclosed
US-5650109-A Method of making reinforcing structural rebar REICHHOLD CHEMICALS, INC. (US) 1997-07-22 US disclosed
EP-0769088-A1 REINFORCING STRUCTURAL REBAR AND METHOD OF MAKING THE SAME MARSHALL INDUSTRIES COMPOSITES (US) 1997-04-23 EP disclosed
WO-1996000824-A1 REINFORCING STRUCTURAL REBAR AND METHOD OF MAKING THE SAME MARSHALL INDUSTRIES COMPOSITES (US) 1996-01-11 WO disclosed
EP-0007779-B1 METHOD OF INCREASING THE VISCOSITY OF A THERMOSET COMPOSITION AND SHAPED ARTICLES MADE FROM THIS COMPOSITION ICI AMERICAS INC. (US) 1983-07-20 EP disclosed
EP-0048117-A2 In-mold coating compositions containing a non-isocyanate-reactive unsaturated resin, a non-isocyanate-reactive monomer and a free isocyanate-containing compound ICI AMERICAS INC. (US) 1982-03-24 EP disclosed
US-4296215-A POLYISOLYANATE TRIMERIZATION, VINYL URETHANE, UNSATURATED POLYESTER CURABLE BLEND ICI AMERICAS INC. (US) 1981-10-20 US disclosed
US-4188349-A Process for curing unsaturated polyesters utilizing novel initiators ICI AMERICAS INC. (US) 1980-02-12 US disclosed
EP-0007779-A1 Method of increasing the viscosity of a thermoset composition and shaped articles made from this composition ICI AMERICAS INC. (US) 1980-02-06 EP disclosed