Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055272 | 1.00 | HCAR2 (0.59) | HCAR2MAPTATMALDH1A1NPSR1 | |
| SCHEMBL11055306 | 1.00 | HCAR2 (0.59) | HCAR2MAPTATMALDH1A1NPSR1 | |
| Diethyl Maleate SCHEMBL11796378 | 0.88 | HCAR2 (0.55) | HCAR2MAPTATMALDH1A1NPSR1 | |
| Diethyl Maleate SCHEMBL28226329 | 0.84 | HCAR2 (0.67) | HCAR2MAPTATMALDH1A1NPSR1 | |
| Diethyl Maleate SCHEMBL4453230 | 0.84 | HCAR2 (0.67) | HCAR2MAPTATMALDH1A1NPSR1 | |
| Diethyl Maleate SCHEMBL4453231 | 0.84 | HCAR2 (0.67) | HCAR2MAPTATMALDH1A1NPSR1 | |
| Diethyl Maleate SCHEMBL5608030 | 0.84 | HCAR2 (0.73) | HCAR2MAPTATMALDH1A1NPSR1 | |
| Diethyl Maleate SCHEMBL20561650 | 0.84 | HCAR2 (0.73) | HCAR2MAPTATMALDH1A1NPSR1 | |
| Diethyl Maleate SCHEMBL5608025 | 0.84 | HCAR2 (0.73) | HCAR2MAPTATMALDH1A1NPSR1 | |
| SCHEMBL5857947 | 0.83 | HCAR2 (0.62) | HCAR2MAPTATMALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6896903-B2 | Bioadhesive compositions | FIRST WATER LIMITED (GB) | 2005-05-24 | — | — | US | claimed |
| EP-1163309-B1 | BIOADHESIVE COMPOSITIONS | FIRST WATER LTD (GB) | 2004-06-09 | — | — | EP | claimed |
| US-20020026005-A1 | Bioadhesive compositions | FIRST WATER LIMITED (GB) | 2002-02-28 | — | — | US | claimed |
| US-20020015689-A1 | Bioadhesive compositions | FIRST WATER LIMITED (GB) | 2002-02-07 | — | — | US | claimed |
| EP-1163309-A1 | BIOADHESIVE COMPOSITIONS | First Water Limited (GB) | 2001-12-19 | — | — | EP | claimed |
| EP-1150721-A1 | BIOADHESIVE COMPOSITIONS | First Water Limited (GB) | 2001-11-07 | — | — | EP | claimed |
| WO-2000046319-A1 | BIOADHESIVE COMPOSITIONS | FIRST WATER LIMITED (GB) | 2000-08-10 | — | — | WO | claimed |
| WO-2000045864-A1 | BIOADHESIVE COMPOSITIONS | FIRST WATER LIMITED (GB) | 2000-08-10 | — | — | WO | claimed |
| EP-1026219-A1 | Bioadhesive compositions | First Water Limited (GB) | 2000-08-09 | — | — | EP | claimed |
| US-7152601-B2 | Strapless respiratory face mask | Barakat, Mohamed Ali (IT) | 2006-12-26 | — | — | US | disclosed |
| EP-1313414-B1 | ANTI-SNORING DEVICE COMPRISING A SKIN COMPATIBLE ADHESIVE | BARAKAT MOHAMED ALI (BE) | 2006-08-23 | — | — | EP | disclosed |
| EP-1357813-B1 | STRAPLESS RESPIRATORY FACE MASK | BARAKAT MOHAMED ALI (IT) | 2006-06-07 | — | — | EP | disclosed |
| US-7055526-B2 | Anti-snoring device comprising a skin compatible adhesive | Bakarat, Mohamed Ali (BE) | 2006-06-06 | — | — | US | disclosed |
| US-6896903-B2 | Bioadhesive compositions | FIRST WATER LIMITED (GB) | 2005-05-24 | — | — | US | disclosed |
| US-5616316-A | REACTING SILICATE WITH ACID TO FORM AQUEOUS SUSPENSION OF SILICA, AGING, SEPARATING | RHONE-POULENC CHIMIE (FR) | 1997-04-01 | — | — | US | disclosed |
| US-5614177-A | FROM SILICATE AND ACID | RHONE-POULENC CHIMIE (FR) | 1997-03-25 | — | — | US | disclosed |
| US-5614176-A | REACTING A SILICATE AND AN ACID | RHONE-POULENC CHIMIE (FR) | 1997-03-25 | — | — | US | disclosed |
| US-5612020-A | SILICATE AND ACID | RHONE-POULENC CHIMIE (FR) | 1997-03-18 | — | — | US | disclosed |
| US-5286478-A | Having unique surface chemistry, specified number of hydroxyl functions and zero charge point | RHONE-POULENC CHIMIE (FR) | 1994-02-15 | — | — | US | disclosed |
| US-4830139-A | Hearing aid holding means and method of using same | CIRILLO EVELYN J (US) | 1989-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020015689-A1 | Bioadhesive compositions | EPCAM, PHOSPHO1, DSG1 | HCAR2 3185/4885MAPT 2393/4885ATM 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.