Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 15/20 | 0.36 |
| ▸ | THRA | P10827 | 14/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250066 | 0.93 | NR3C1 (0.56) | NR3C1THRBTHRARORC | |
| SCHEMBL7257207 | 0.85 | NR3C1 (0.51) | NR3C1THRBTHRARORCLPAR1 | |
| SCHEMBL7251532 | 0.79 | NR3C1 (0.62) | NR3C1THRBTHRARORCLMNA | |
| SCHEMBL7254262 | 0.78 | NR3C1 (0.56) | NR3C1THRBTHRARORCLPAR1 | |
| SCHEMBL7251618 | 0.78 | NR3C1 (0.52) | NR3C1THRBTHRA | |
| SCHEMBL7050482 | 0.78 | NR3C1 (0.55) | NR3C1THRBTHRARORCLMNA | |
| SCHEMBL7254849 | 0.78 | NR3C1 (0.44) | NR3C1THRBTHRARORC | |
| SCHEMBL7250323 | 0.77 | NR3C1 (0.61) | NR3C1THRBTHRA | |
| SCHEMBL7250689 | 0.77 | NR3C1 (0.61) | NR3C1THRBTHRARORC | |
| SCHEMBL7252303 | 0.77 | NR3C1 (0.59) | NR3C1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265839-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR | KARO BIO AB (SE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001047859-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR | KARO BIO AB (SE) | 2001-07-05 | — | — | WO | disclosed |