Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL2208770 | 0.90 | TSHR (0.67) | TSHRMMP3BCL2L1CHRM2ESR2 | |
| SCHEMBL675866 | 0.90 | TSHR (0.73) | TSHRCHRM2KDM1AMAOBTAAR1 | |
| SCHEMBL10300819 | 0.90 | TSHR (0.73) | TSHRCHRM2KDM1AMAOBTAAR1 | |
| SCHEMBL2063957 | 0.85 | TSHR (0.56) | TSHRKDM1AESR1MEN1KMT2A | |
| SCHEMBL2063039 | 0.85 | TSHR (0.56) | TSHRKDM1AESR1MEN1KMT2A | |
| Biphenyl SCHEMBL8064797 | 0.83 | TSHR (0.85) | TSHRCHRM2MEN1KMT2A | |
| SCHEMBL867412 | 0.81 | TSHR (0.62) | TSHRCHRM2TAAR1 | |
| SCHEMBL10070384 | 0.79 | TSHR (0.57) | TSHRCHRM2KDM1AMEN1KMT2A | |
| SCHEMBL279278 | 0.79 | TSHR (0.57) | TSHRCHRM2KDM1AMEN1KMT2A | |
| Hydrogen Peroxide SCHEMBL28927927 | 0.79 | TSHR (0.94) | TSHRCHRM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151659-A1 | Formed from 6,6'-bis(2-(4-fluorophenyl)-4- phenylquinoline) and 4,4'-(1,1,1,3,3,3-hexafluoro-2,2-propylidene)bisphenol and 2,2-bis((4-maleimidophenoxy)phenyl)propane; dielectrics | HITACHI CHEMICAL CO., LTD. (JP) | 2002-10-17 | — | — | US | disclosed |
| US-6462148-B1 | RESIN COMPOSITION COMPRISING A POLYMER CONTAINING A QUINOLINE RING AND A THERMOSETTING RESIN, AN INSULATING MATERIAL CONSTITUTED BY SAID RESIN COMPOSITION AND AN ADHESIVE FILM, PARTICULARLY A RESIN FOR AN INTERLAYER INSULATION FILM | HITACHI CHEMICAL CO., LTD. (JP) | 2002-10-08 | — | — | US | disclosed |