SCHEMBL867412

SCHEMBL867412

c1cc(C2CO2)ccc1-c1ccc(C2CO2)cc1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.62
CHRM2 P08172 6/20 0.49
ADRA2A P08913 3/20 0.37
CHRM3 P20309 3/20 0.37
CHRM4 P08173 2/20 0.37
CHRM1 P11229 2/20 0.37
PARP1 P09874 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
GSTO1 P78417 1/20 0.35
CHRM5 P08912 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL46155 0.91 TSHR (0.72) TSHRCHRM2ADRA2ACHRM3CHRM4
SCHEMBL10300819 0.90 TSHR (0.73) TSHRCHRM2ADRA2ACHRM3CHRM4
SCHEMBL11825405 0.81 CHRM2 (0.45) TSHRCHRM2CHRM3CHRM4CHRM1
SCHEMBL10070384 0.79 TSHR (0.57) TSHRCHRM2ADRA2ACHRM3CHRM4
SCHEMBL13266330 0.79 TSHR (0.57) TSHRCHRM2ADRA2ACHRM3CHRM4
SCHEMBL279278 0.79 TSHR (0.57) TSHRCHRM2ADRA2ACHRM3CHRM4
SCHEMBL1120426 0.78 TSHR (0.56) TSHRCHRM2CHRM3CHRM4CHRM1
SCHEMBL531416 0.78 TSHR (0.56) TSHRTAAR1GSTO1
SCHEMBL13450817 0.78 TSHR (0.56) TSHRCHRM2ADRA2ACHRM3CHRM4
SCHEMBL14524330 0.78 TSHR (0.56) TSHRCHRM2ADRA2ACHRM3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3931238-A1 CROSS-LINKABLE NETWORK FROM FUNCTIONALIZED POLYETHERIMIDE AND THERMOSET POLYMER RESULTING THEREFROM SHPP Global Technologies B.V. (NL) 2022-01-05 EP claimed
US-4448940-A POLYOXAZOLINES BASED ON DINITRILES AND DIEPOXY COMPOUNDS; POLYISOCYANURATE; FLEXIBILITY; PRINTED CIRCUITS HITACHI, LTD. (JP) 1984-05-15 US claimed
US-4384101-A EPOXIDE, ISOCYANATE, TRIALLYL CYANURATE AS CROSSLINKER FOR THERMOSETTING ELECTRICAL INSULATION BBC BROWN, BOVERI & COMPANY, LIMITED (CH) 1983-05-17 US claimed
CN-116675953-A Crosslinkable Networks and Thermoset Polymers from Functionalized Polyetherimides 高新特殊工程塑料全球技术有限公司 2023-09-01 CN disclosed
CN-113710725-B Crosslinkable networks from functionalized polyetherimides and thermoset polymers therefrom 高新特殊工程塑料全球技术有限公司 2023-07-07 CN disclosed
CN-112585183-B Polyisocyanurate raw material composition and process for producing polyisocyanurate 昭和电工株式会社 2023-04-18 CN disclosed
US-11584821-B2 Raw material composition for polyisocyanurate and method for producing polyisocyanurate SHOWA DENKO K.K. (JP) 2023-02-21 US disclosed
US-20220145065-A1 CROSS-LINKABLE NETWORK FROM FUNCTIONALIZED POLYETHERIMIDE AND THERMOSET POLYMER RESULTING THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-12 US disclosed
US-20210292462-A1 RAW MATERIAL COMPOSITION FOR POLYISOCYANURATE AND METHOD FOR PRODUCING POLYISOCYANURATE SHOWA DENKO K.K. (JP) 2021-09-23 US disclosed
WO-2020166646-A1 RAW MATERIAL COMPOSITION FOR POLYISOCYANURATES AND PRODUCTION METHOD FOR POLYISOCYANURATES 昭和電工株式会社 2020-08-20 WO disclosed
US-20160289491-A1 3D PRINTABLE LQUID CRYSTALLINE ELASTOMERS WITH TUNABLE SHAPE MEMORY BEHAVIOR AND BIO-DERIVED RENDITIONS U. S. DEPARTMENT OF ENERGY 2016-10-06 US disclosed
US-4269894-A AS BINDERS FOR THE MULTILAYERED INSULATION; IMPREGNATING WITH A VARNISH OF EPOXY-ISOCYANATE RESIN; WATERPROOFING HITACHI, LTD. (JP) 1981-05-26 US disclosed
US-4222802-A SILICONE RESIN INSULATOR, IMPREGNATING WITH VARNISH OF AN EPOXY COMPOUND AND AN ISOCYANATE COMPOUND, CURING HITACHI, LTD. (JP) 1980-09-16 US disclosed
EP-0012566-A1 Electric windings and production thereof Hitachi, Ltd. (JP) 1980-06-25 EP disclosed
US-4132697-A LIQUID IMPREGNANT AS A FIBER REINFORCING BINDER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-01-02 US disclosed
US-4070416-A POLYFUNCTIONAL ISOCYANATES AND EPOXIDES, ISOCYANURATE-OXAZOLIDOLE POLYMERS HITACHI, LTD. (JA) 1978-01-24 US disclosed
US-4041004-A Polyepoxy-3,3',4,4'-benzhydrol tetracarboxylic dianhydride laminating resins GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-08-09 US disclosed
US-3996185-A Polyepoxy resin-diaryl dianhydride laminating resins and laminates GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-12-07 US disclosed
US-3984376-A Thermosetting resin compositions prepared from isocyanates and epoxyphenols HITACHI, LTD. (JA) 1976-10-05 US disclosed
US-3932557-A Reactive hydrophilic epoxy containing polymer GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292462-A1 RAW MATERIAL COMPOSITION FOR POLYISOCYANURATE AND METHOD FOR PRODUCING POLYISOCYANURATE PUF60, ALKBH3, PCBP1 TSHR 4621/4885CHRM2 1800/4885ADRA2A 3770/4885
US-11584821-B2 Raw material composition for polyisocyanurate and method for producing polyisocyanurate PUF60, ALKBH3, PCBP1 TSHR 4621/4885CHRM2 1800/4885ADRA2A 3770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.