Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | GYS1 | P13807 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612371 | 0.91 | VDR (0.43) | VDRFFAR1MMP12ADRB3STAT3 | |
| SCHEMBL7647800 | 0.87 | VDR (0.39) | VDRS1PR1S1PR5STAT3 | |
| SCHEMBL7610479 | 0.84 | VDR (0.35) | VDRFFAR1GYS1S1PR1S1PR5 | |
| SCHEMBL7607763 | 0.82 | VDR (0.46) | VDRFFAR1GYS1S1PR1S1PR5 | |
| SCHEMBL7610506 | 0.82 | VDR (0.43) | VDRFFAR1MMP12GYS1 | |
| SCHEMBL7606371 | 0.82 | FFAR1 (0.47) | VDRFFAR1 | |
| SCHEMBL7606177 | 0.82 | VDR (0.54) | VDRFFAR1MMP12GYS1S1PR1 | |
| SCHEMBL7606746 | 0.81 | VDR (0.35) | VDRFFAR1 | |
| SCHEMBL7610505 | 0.79 | VDR (0.43) | VDRFFAR1 | |
| SCHEMBL7607689 | 0.79 | VDR (0.44) | VDRFFAR1S1PR1S1PR5PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | claimed |