Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612427 | 0.89 | CD274 (0.40) | CD274FFAR4PDCD1FFAR1 | |
| SCHEMBL7606742 | 0.88 | VDR (0.35) | VDRCD274RXRARXRBRXRG | |
| SCHEMBL7610505 | 0.82 | VDR (0.43) | VDRCD274FFAR4FFAR1 | |
| SCHEMBL7607763 | 0.82 | VDR (0.46) | VDRFFAR4FFAR1STAT3 | |
| SCHEMBL7610506 | 0.82 | VDR (0.43) | VDRFFAR4FFAR1 | |
| SCHEMBL7606748 | 0.82 | VDR (0.35) | VDRCD274RXRARXRBRXRG | |
| SCHEMBL7606177 | 0.81 | VDR (0.54) | VDRFFAR4FFAR1 | |
| SCHEMBL7606371 | 0.80 | FFAR1 (0.47) | VDRFFAR4FFAR1 | |
| SCHEMBL6563072 | 0.79 | VDR (0.53) | VDRCD274RXRARXRBRXRG | |
| SCHEMBL7615205 | 0.79 | VDR (0.52) | VDRSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |