Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605055 | 0.96 | CHRM2 (0.36) | PIK3CDLMNACA12CA1CA2 | |
| SCHEMBL7606762 | 0.94 | CHRM2 (0.35) | PIK3CDLMNACA12CA1CA2 | |
| SCHEMBL7603122 | 0.87 | PIK3CD (0.37) | PIK3CDLMNACA12CA1CA2 | |
| SCHEMBL7605032 | 0.84 | ACHE (0.32) | — | |
| SCHEMBL7605230 | 0.83 | CHRM2 (0.35) | PIK3CDLMNACA12CA1CA2 | |
| SCHEMBL7608770 | 0.83 | — | — | |
| SCHEMBL7607202 | 0.83 | PIK3CD (0.45) | PIK3CDLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL7603856 | 0.82 | CHRM2 (0.35) | PIK3CDLMNACA12CA1CA2 | |
| SCHEMBL1705435 | 0.82 | PIK3CD (0.53) | PIK3CDLMNACA12CA1CA2 | |
| SCHEMBL7603177 | 0.79 | PIK3CD (0.50) | PIK3CDLMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934080-B1 | 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF | BASF AG (DE) | 2002-06-12 | — | — | EP | claimed |
| EP-0934080-B1 | 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF | BASF AG (DE) | 2002-06-12 | — | — | EP | disclosed |