⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031094 | 0.72 | CSNK2A2 (0.41) | — | |
| SCHEMBL633410 | 0.65 | CSNK2A2 (0.41) | — | |
| SCHEMBL11716446 | 0.62 | CSNK2A2 (0.39) | — | |
| SCHEMBL6293796 | 0.61 | — | — | |
| SCHEMBL1830346 | 0.61 | — | — | |
| SCHEMBL5363779 | 0.61 | — | — | |
| SCHEMBL12948673 | 0.61 | — | — | |
| SCHEMBL2079526 | 0.60 | — | — | |
| SCHEMBL9483459 | 0.59 | — | — | |
| SCHEMBL9333206 | 0.57 | APEX1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052511-A1 | Process for the preparation of matrix metalloproteinase inhibitors | BAILEY ANNE E (US) | 2002-05-02 | — | — | US | claimed |
| US-20020019539-A1 | Process for the preparation of matrix metalloproteinase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | claimed |
| US-7488824-B2 | Process for the production of substituted nicotinic acid esters | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-7488824-B2 | Process for the production of substituted nicotinic acid esters | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-6441189-B1 | WHICH REDUCES RACEMIZATION; (4R)-4-(HYDROXYMETHYL)-1,3-OXAZOLIDIN-2-ONE BY REDUCTION AND BASIFICATION OF THE CORRESPONDING 4-PROTECTED CARBOXY ESTER | ABBOTT LABORATORIES | 2002-08-27 | — | — | US | disclosed |
| US-20020052511-A1 | Process for the preparation of matrix metalloproteinase inhibitors | BAILEY ANNE E (US) | 2002-05-02 | — | — | US | disclosed |
| US-20020019539-A1 | Process for the preparation of matrix metalloproteinase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |