Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607108 | 1.00 | ALDH1A1 (0.38) | ALDH1A1PABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL7614042 | 0.82 | NTRK1 (0.41) | — | |
| SCHEMBL7614047 | 0.82 | NTRK1 (0.41) | — | |
| SCHEMBL7606157 | 0.80 | JAK3 (0.41) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5873743 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL7606158 | 0.80 | JAK3 (0.41) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5873740 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL7613347 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1JMJD6MDM2MEN1NPC1 | |
| SCHEMBL7613340 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1JMJD6MDM2MEN1NPC1 | |
| SCHEMBL5873824 | 0.78 | ALDH1A1 (0.37) | ALDH1A1PABPC1APOBEC3AEIF4HAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099071-A1 | Protein tyrosine kinase and protein serin/threonine kinase inhibitory activity; anticancer agents; treating chemotherapy induced alopecia | GLENNON KIMBERLEY CAROLINE (US) | 2002-07-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099071-A1 | Protein tyrosine kinase and protein serin/threonine kinase inhibitory activity; anticancer agents; treating chemotherapy induced alopecia | PRKDC, PRKX, BMX | ALDH1A1 4171/4885PABPC1 2822/4885APOBEC3A 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.