Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.53 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395188 | 0.87 | HDAC6 (0.69) | HDAC1HDAC6HDAC2HDAC8PPARG | |
| SCHEMBL11593046 | 0.87 | PTGS1 (0.75) | PTGS1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL7605130 | 0.85 | PTGS1 (0.60) | PTGS1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL7606673 | 0.85 | EPHX2 (0.68) | HDAC1HDAC6HDAC2HDAC8PPARG | |
| Hydrochloric Acid SCHEMBL5094385 | 0.84 | PRSS1 (0.57) | NAMPTHDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL1352405 | 0.83 | PTGS1 (0.68) | PTGS1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2127722 | 0.83 | PTGS1 (0.77) | PTGS1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL27952268 | 0.82 | LMNA (0.70) | NAMPTHDAC6HDAC2HDAC8PPARG | |
| SCHEMBL4161846 | 0.82 | HDAC6 (0.60) | NAMPTHDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL5592556 | 0.81 | PTGS1 (0.60) | PTGS1NAMPTHDAC1HDAC2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | PTGS1 361/4885NAMPT 1448/4885HDAC1 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.