Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 15/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377637 | 0.83 | FOLH1 (0.50) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7604450 | 0.82 | FOLH1 (0.47) | FOLH1GRM3NAALAD2 | |
| SCHEMBL108166 | 0.77 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 | |
| SCHEMBL10430532 | 0.76 | FOLH1 (0.61) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7145291 | 0.76 | FOLH1 (0.52) | FOLH1GRM3NAALAD2 | |
| SCHEMBL10045696 | 0.75 | KDM4C (0.48) | — | |
| SCHEMBL13726298 | 0.75 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL29060942 | 0.75 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL27996973 | 0.75 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7607491 | 0.74 | FOLH1 (0.50) | FOLH1GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514185-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-0949922-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING COMPULSIVE DISORDERS USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-10-20 | — | — | EP | claimed |
| WO-1998013044-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING COMPULSIVE DISORDERS USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |