Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591698 | 0.77 | KDM4E (0.62) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL647157 | 0.77 | KDM4E (0.62) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL1600830 | 0.75 | KDM4E (0.65) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL11114285 | 0.75 | KDM4E (0.65) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL7615520 | 0.74 | MEN1 (0.51) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL11114287 | 0.73 | MAPT (0.68) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL9347143 | 0.73 | KDM4E (0.62) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL17186177 | 0.73 | KDM4E (0.57) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL4765694 | 0.71 | KDM4E (0.69) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL12359712 | 0.71 | KDM4E (0.59) | KDM4EGAAMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198254-A1 | Polyamide analogs | GENELABS TECHNOLOGIES, INC. | 2002-12-26 | — | — | US | claimed |
| WO-2002062755-A2 | POLYAMIDE ANALOGS AS DNA MINOR GROOVE BINDERS | GENELABS TECHNOLOGIES, INC. (US) | 2002-08-15 | — | — | WO | claimed |
| US-20020198254-A1 | Polyamide analogs | GENELABS TECHNOLOGIES, INC. | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198254-A1 | Polyamide analogs | CYP51A1, HDAC6, ERG28 | KDM4E 3634/4885GAA 8/4885MAPT 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.