Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 7/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31390461 | 0.86 | TSHR (0.50) | TSHRACHENAAADGKAHPGD | |
| SCHEMBL31390459 | 0.85 | TSHR (0.53) | TSHRACHENAAAHPGDALDH1A1 | |
| SCHEMBL9546259 | 0.84 | TSHR (0.47) | TSHRACHEDGKAHPGDALDH1A1 | |
| SCHEMBL1138993 | 0.84 | TSHR (0.43) | TSHRACHEDGKAHPGDALDH1A1 | |
| SCHEMBL1270266 | 0.83 | TSHR (0.61) | TSHRACHENAAADGKAALDH1A1 | |
| SCHEMBL8525995 | 0.83 | TSHR (0.40) | TSHRACHEDGKAHPGDALDH1A1 | |
| SCHEMBL170886 | 0.82 | TSHR (0.52) | TSHRACHENAAADGKAHPGD | |
| SCHEMBL6916133 | 0.82 | CES1 (0.46) | TSHRALDH1A1CES2CES1 | |
| SCHEMBL16208006 | 0.81 | TSHR (0.44) | TSHRNAAADGKAHPGDALDH1A1 | |
| SCHEMBL2364287 | 0.81 | TSHR (0.49) | TSHRACHEDGKAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232212-A1 | COMPOSITION AND METHOD FOR COLOR IMPROVEMENT OF NITROXYL CONTAINING POLYMERS | Ciba SC Holding AG (CH) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001038431-A1 | COMPOSITION AND METHOD FOR COLOR IMPROVEMENT OF NITROXYL CONTAINING POLYMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-05-31 | — | — | WO | disclosed |