Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606577 | 1.00 | CTSV (0.44) | CTSVCTSLPOLBPDCD1CD274 | |
| SCHEMBL7604658 | 0.93 | MAPT (0.44) | CTSVCTSLPOLBPDCD1CD274 | |
| SCHEMBL7605323 | 0.92 | CTSV (0.43) | CTSVCTSLPOLBPDCD1CD274 | |
| SCHEMBL7605039 | 0.92 | CTSV (0.42) | CTSVCTSLPOLBPDCD1CD274 | |
| SCHEMBL7609869 | 0.88 | CTSV (0.40) | CTSVCTSLPOLBPDCD1CD274 | |
| SCHEMBL7604989 | 0.87 | MEN1 (0.47) | CTSVCTSLABCB1FFAR1MAPT | |
| SCHEMBL7608520 | 0.85 | FFAR1 (0.40) | CTSVCTSLPDCD1CD274ABCB1 | |
| SCHEMBL7609320 | 0.84 | CTSV (0.44) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL7699817 | 0.84 | CTSV (0.44) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL7605016 | 0.83 | MAPT (0.43) | CTSVCTSLPOLBPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |