Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611564 | 0.87 | ACP1 (0.49) | ACP1PTPN12PTPN13SSU72MRGPRX4 | |
| SCHEMBL7604647 | 0.85 | BACE1 (0.46) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7606227 | 0.80 | HDAC3 (0.51) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL8127646 | 0.73 | HDAC1 (0.53) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL24323598 | 0.73 | BACE1 (0.62) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL38659146 | 0.73 | ACP1 (0.53) | ACP1PTPN12PTPN13SSU72MRGPRX4 | |
| SCHEMBL29059512 | 0.73 | BACE1 (0.62) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL15311357 | 0.72 | HDAC3 (0.52) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL18191672 | 0.72 | HDAC3 (0.55) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL24324611 | 0.72 | HDAC3 (0.52) | BACE1HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |