Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.74 |
| ▸ | NOS2 | P35228 | 11/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491411 | 0.85 | SLC6A4 (1.00) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| Hydrochloric Acid SCHEMBL6504301 | 0.84 | SLC6A4 (0.98) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| Fumaric Acid SCHEMBL6492078 | 0.78 | SLC6A4 (0.87) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| Fumaric Acid SCHEMBL6493113 | 0.78 | SLC6A4 (0.87) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| SCHEMBL6500819 | 0.76 | NOS2 (0.73) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| SCHEMBL6500811 | 0.73 | NOS2 (0.71) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| SCHEMBL6500144 | 0.72 | SLC6A2 (0.77) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| SCHEMBL20435479 | 0.71 | SLC6A4 (1.00) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| SCHEMBL6504695 | 0.71 | SLC6A4 (0.75) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| Hydrochloric Acid SCHEMBL6502850 | 0.71 | SLC6A2 (0.77) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263711-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062704-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |