Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686667 | 0.85 | MAPT (0.41) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL30022924 | 0.78 | MAPT (0.41) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL27326052 | 0.76 | POLB (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL2332847 | 0.72 | ALDH1A1 (0.68) | ALDH1A1CYP1A2CYP2C9CYP2C19TDP1 | |
| SCHEMBL4299519 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL9707193 | 0.72 | DNMT1 (0.42) | ALDH1A1MAPTTDP1CYP2A6TSHR | |
| SCHEMBL18320175 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL31543984 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL6310662 | 0.71 | TSHR (0.56) | ALDH1A1CYP1A2MAPTTDP1CYP2A6 | |
| SCHEMBL11797328 | 0.70 | HPRT1 (0.54) | ALDH1A1CYP1A2CYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672675-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2002-07-24 | — | — | EP | disclosed |