SCHEMBL7608060

SCHEMBL7608060

CC(C)(C)CC(=CC=Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.57
CYP2C19 P33261 1/20 0.44
MCL1 Q07820 2/20 0.43
EGFR P00533 1/20 0.42
MAOB P27338 1/20 0.42
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 4/20 0.41
ALDH1A1 P00352 4/20 0.41
TRPA1 O75762 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPK1 P28482 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3804001 0.89 GRIK1 (0.48) GRIK1CYP2C19MCL1EGFRGLA
SCHEMBL10394714 0.83 GRIK1 (0.60) GRIK1MCL1MAOBGLATDP1
SCHEMBL221210 0.83 GRIK1 (0.60) GRIK1MCL1MAOBGLATDP1
SCHEMBL491485 0.81 CYP3A4 (0.58) CYP2C19EGFRGLATDP1LMNA
SCHEMBL293503 0.80 GRIK1 (0.57) GRIK1MCL1MAOBGLATDP1
SCHEMBL5031405 0.79 GRIK1 (0.60) GRIK1MCL1MAOBGLATDP1
SCHEMBL5597302 0.79 GRIK1 (0.60) GRIK1MCL1MAOBGLATDP1
SCHEMBL10334374 0.79 GRIK1 (0.60) GRIK1MCL1MAOBGLATDP1
SCHEMBL5478415 0.78 PAM (0.59) GRIK1MCL1MAOBLMNAALDH1A1
SCHEMBL1905164 0.78 CYP3A4 (0.64) GRIK1MCL1MAOBLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11258047-B2 Organic electroluminescent element and measurement apparatus HAMAMATSU PHOTONICS K.K. (JP) 2022-02-22 US disclosed
US-20200313120-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND MEASUREMENT APPARATUS HAMAMATSU PHOTONICS K.K. (JP) 2020-10-01 US disclosed
US-8580374-B2 Resin molded body HAMAMATSU PHOTONICS K.K. (JP) 2013-11-12 US disclosed
US-8507079-B2 Structural color body HAMAMATSU PHOTONICS K.K. (JP) 2013-08-13 US disclosed
US-8440294-B2 Structural color body HAMAMATSU PHOTONICS K.K. (JP) 2013-05-14 US disclosed
US-8394490-B2 Structural color body HAMAMATSU PHOTONICS K.K. (JP) 2013-03-12 US disclosed
US-20130004721-A1 STRUCTURAL COLOR BODY HAMAMATSU PHOTONICS K.K. (JP) 2013-01-03 US disclosed
US-20130004722-A1 RESIN MOLDED BODY HAMAMATSU PHOTONICS K.K. (JP) 2013-01-03 US disclosed
US-20130004754-A1 STRUCTURAL COLOR BODY HAMAMATSU PHOTONICS K.K. (JP) 2013-01-03 US disclosed
US-20130004731-A1 STRUCTURAL COLOR BODY HAMAMATSU PHOTONICS K.K. (JP) 2013-01-03 US disclosed
US-20020010107-A1 Perfume composition for laundry detergent TAKASAGO INTERNATIONAL CORPORATION 2002-01-24 US disclosed
US-5397841-A Grafted polymers having reactive groups at the base SHELL OIL COMPANY (US) 1995-03-14 US disclosed
EP-0569100-A1 Polymers having stable anhydride rings SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-11-10 EP disclosed
US-5218053-A Anionically polymerizing conjugated alkadienes or alkenyl aromatics and an unsaturated ester; hydrogenating; heating to cyclize SHELL OIL COMPANY (US) 1993-06-08 US disclosed