Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | PDXK | O00764 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970326 | 0.81 | HPGD (0.70) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL18912675 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Pyridoxine SCHEMBL20502352 | 0.78 | KDM4E (0.92) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Pyridoxine SCHEMBL2322958 | 0.78 | HPGD (1.00) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Pyridoxine SCHEMBL30267871 | 0.78 | HPGD (1.00) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Pyridoxine SCHEMBL3506 | 0.78 | HPGD (1.00) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Pyridoxine SCHEMBL30877002 | 0.78 | HPGD (1.00) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Pyridoxine SCHEMBL28837806 | 0.77 | KDM4E (0.89) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL30649291 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL22446367 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10PDXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020164651-A1 | Diagnostic for inflammatory diseases associated with cartilage and bone surfaces | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-07 | — | — | US | disclosed |