Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595012 | 0.88 | MEN1 (0.42) | LTA4HS1PR1S1PR3S1PR5MEN1 | |
| SCHEMBL3595010 | 0.88 | MEN1 (0.42) | LTA4HS1PR1S1PR3S1PR5MEN1 | |
| SCHEMBL3595016 | 0.88 | MEN1 (0.42) | LTA4HS1PR1S1PR3S1PR5MEN1 | |
| SCHEMBL3598408 | 0.85 | LTA4H (0.44) | LTA4HS1PR1MEN1POLBPKM | |
| SCHEMBL3598347 | 0.85 | LTA4H (0.44) | LTA4HS1PR1MEN1POLBPKM | |
| SCHEMBL3598346 | 0.85 | LTA4H (0.44) | LTA4HS1PR1MEN1POLBPKM | |
| SCHEMBL13443457 | 0.84 | MEN1 (0.36) | LTA4HS1PR1MEN1POLBPKM | |
| SCHEMBL2691155 | 0.84 | KMT2A (0.39) | LTA4HS1PR1MEN1POLBPKM | |
| SCHEMBL2691150 | 0.84 | KMT2A (0.39) | LTA4HS1PR1MEN1POLBPKM | |
| SCHEMBL3606248 | 0.84 | MEN1 (0.42) | S1PR1MEN1POLBPKMBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216223-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES WITH PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019778-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES WITH PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |