Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.61 |
| ▸ | CTSB | P07858 | 6/20 | 0.61 |
| ▸ | CTSS | P25774 | 2/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.61 |
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007938 | 1.00 | CTSL (0.61) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10795546 | 1.00 | CTSL (0.61) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11199738 | 0.95 | CTSL (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL29480462 | 0.95 | CTSL (0.66) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL6440666 | 0.90 | CTSL (0.64) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL6440663 | 0.90 | CTSL (0.64) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7030418 | 0.88 | CTSL (0.50) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11057901 | 0.88 | CTSL (0.58) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10727026 | 0.88 | MME (0.67) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL20678118 | 0.88 | MME (0.67) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002512960-A | — | — | 2002-05-08 | — | — | JP | claimed |
| EP-1073434-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-02-07 | — | — | EP | claimed |
| WO-1999055330-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-04 | — | — | WO | claimed |
| EP-1073434-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055330-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-04 | — | — | WO | disclosed |