SCHEMBL7608601

SCHEMBL7608601

O=C(O)/C=C/c1ccc(OCCCCCCCCO)cc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.54
ATM Q13315 1/20 0.54
PPARA Q07869 4/20 0.54
TBXAS1 P24557 2/20 0.53
ALB P02768 1/20 0.52
POLB P06746 1/20 0.51
BCHE P06276 2/20 0.49
ACHE P22303 2/20 0.49
LSS P48449 1/20 0.48
APP P05067 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6873476 1.00 THRB (0.54) THRBATMPPARATBXAS1ALB
SCHEMBL2223771 1.00 THRB (0.54) THRBATMPPARATBXAS1ALB
SCHEMBL7608605 1.00 THRB (0.54) THRBATMPPARATBXAS1ALB
SCHEMBL2223776 1.00 THRB (0.54) THRBATMPPARATBXAS1ALB
SCHEMBL7607106 0.98 THRB (0.56) THRBATMPPARATBXAS1ALB
SCHEMBL7607101 0.98 THRB (0.56) THRBATMPPARATBXAS1ALB
SCHEMBL11685417 0.94 THRB (0.57) THRBATMPPARATBXAS1POLB
SCHEMBL14686124 0.94 THRB (0.57) THRBATMPPARATBXAS1POLB
SCHEMBL17061289 0.93 SRD5A2 (0.58) THRBATMPPARATBXAS1BCHE
SCHEMBL17061272 0.93 SRD5A2 (0.58) THRBATMPPARATBXAS1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6461694-B1 OPTICAL COMPENSATORY SHEET COMPRISING, IN THIS ORDER, TRANSPARENT SUPPORT, ORIENTATION LAYER, AND OPTICALLY ANISOTROPIC LAYER FORMED FROM SPECIFIED DISCOTIC LIQUID CRYSTAL MOLECULES AND HAVING HIGH REFRACTIVE ANISOTROPY FUJI PHOTO FILM CO., LTD. (JP) 2002-10-08 US disclosed